Aromasin (Exemestane)

Common Use

Aromasin contains the active ingredient exemestane, which belongs to a class of medications called aromatase inhibitors—in simple terms, it works by blocking an enzyme called aromatase, which is responsible for producing estrogen in the body after menopause. Many types of breast cancer are hormone receptor-positive, meaning they depend on estrogen to grow and spread. By lowering estrogen levels, Aromasin helps slow or stop the growth of certain breast tumors.

Aromasin is used primarily to treat:

Early-stage hormone receptor-positive breast cancer in postmenopausal women—often after 2–3 years of tamoxifen therapy (sequential treatment)

Advanced (metastatic) breast cancer in postmenopausal women—when other hormone therapies (such as tamoxifen) have stopped working

As a first-line treatment for advanced breast cancer in postmenopausal women

Aromasin is specifically for postmenopausal women and is not effective in women who still have regular menstrual periods.

Dosage and Direction

The usual recommended dose is 25 mg (one tablet) once daily, taken after a meal—taking it with food helps with absorption and may reduce stomach upset. It is best to take it at the same time each day to maintain consistent levels in your body.

Follow your doctor’s prescription carefully and do not change the dose without consulting your healthcare provider. Treatment may continue for several years, depending on your condition.

Precautions

Before taking Aromasin, inform your doctor if you have:

Liver disease – the medication is processed by the liver

Kidney disease – dose adjustments may be needed

Osteoporosis or low bone mineral density – because Aromasin lowers estrogen, it can accelerate bone thinning

High cholesterol – Aromasin may affect cholesterol levels

Pregnancy and birth control:

Aromasin is for postmenopausal women only. However, if you are still of childbearing potential, use effective birth control during treatment, as the drug may cause harm to an unborn baby

Do not use Aromasin if you are pregnant or breastfeeding

Driving and operating machinery:

Avoid driving or operating machinery if you experience dizziness, fatigue, or drowsiness while taking this medication

Contraindications

Aromasin should not be used in the following situations:

Premenopausal women – it is not effective and may not be safe

Pregnancy or breastfeeding

Known hypersensitivity (allergy) to exemestane or any of its components

Possible Side Effects

Common side effects may include:

Hot flashes – sudden feelings of warmth, often in the face and chest

Headache

Fatigue (tiredness)

Nausea

Increased sweating

Joint or muscle pain (arthralgia)

Insomnia (trouble sleeping)

Mood changes

Less common but more serious side effects may include:

Bone loss (osteoporosis) – leading to an increased risk of fractures

Depression – mood changes that may be severe

Liver function changes – symptoms may include yellowing of the skin or eyes (jaundice), dark urine, or severe abdominal pain

Severe allergic reactions – rash, swelling, difficulty breathing

Carpal tunnel syndrome – numbness or tingling in the hands and fingers

If you experience any severe or persistent symptoms, contact your doctor immediately.

Drug Interactions

Aromasin may interact with several medications. Always inform your doctor about all medications and supplements you are taking, including over-the-counter products and herbal remedies.

Important interactions:

Estrogen-containing medications – such as hormone replacement therapy (HRT) or estrogen-based contraceptives, which can reduce or neutralize the effects of Aromasin

Drugs that affect liver enzymes – such as:

Rifampicin (an antibiotic)

Phenytoin or carbamazepine (seizure medications)

St. John’s wort (an herbal supplement) – these may decrease the effectiveness of Aromasin

Missed Dose

If you miss a dose, take it as soon as you remember—unless it is almost time for your next dose. If that’s the case, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

Overdose

In case of overdose, seek immediate medical attention. Symptoms may include:

Severe dizziness

Vomiting

Loss of consciousness

There is no specific antidote for Aromasin overdose; treatment is supportive and symptomatic.

Storage

Store Aromasin at room temperature between 15–30°C (59–86°F), away from moisture and heat. Keep it out of reach of children and pets.

Disclaimer

We provide only general information about medications, which does not cover all directions, possible drug interactions, or precautions. Information on this site cannot be used for self-treatment or self-diagnosis. Any specific instructions for a particular patient should be agreed upon with your healthcare adviser or the doctor in charge of your case. We disclaim reliability of this information and any mistakes it may contain. We are not responsible for any direct, indirect, special, or other indirect damage as a result of any use of the information on this site, nor for the consequences of self-treatment.

About Our Service Cydoctors.com is an online pharmacy based right here in Cyprus. We understand that breast cancer treatment is a deeply personal journey, and having reliable, consistent access to your medication is absolutely essential—so we’ve made our service straightforward, dependable, and built with your peace of mind in mind. Because we’re local to the island, we can arrange delivery in the shortest possible time. For our customers in Nicosia, Limassol, and Larnaca, we’re pleased to offer overnight delivery, so your Aromasin can be with you by the next day, helping you stay on track with your treatment and focus on what matters most—your health and wellbeing.